The BMJ: Leading Medical Research, News, Education, Opinion
WEBHigh impact medical journal. Champion of better research, clinical practice & healthcare policy since 1840. For GPs, hospital doctors, educators, policymakers.
Interpreting raised serum ferritin levels | The BMJ
WEBAug 3, 2015 · Ferritin is an intracellular iron storage protein and a marker of iron stores. Normal serum ferritin levels vary between laboratories but generally concentrations >300 µg/L in men and postmenopausal women and >200 µg/L in premenopausal women are regarded as elevated. 1 Low ferritin values provide …
Interpreting iron studies | The BMJ
WEBJun 15, 2017 · Box 1: Suggested indications for iron studies. Investigation of. iron overload (haemochromatosis) 1. o at early stages can be asymptomatic or present with vague symptoms such as fatigue, weakness, or generalised joint pains. o later manifestations might include deranged liver enzymes, cirrhosis, erectile dysfunction, arthritis, or cardiomyopathy.
Acute coronary syndromes: summary of updated NICE guidance
WEBJan 15, 2021 · Acute coronary syndromes (ACS), comprising ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina, are an important cause of morbidity and mortality in the UK and worldwide. 1 The National Institute for Health and Care Excellence (NICE) previously published four guidelines to improve care for people in the UK who have had an ACS. 2 3 4 ...
Pregabalin and gabapentin for pain | The BMJ
WEBApr 28, 2020 · Pregabalin and gabapentin, collectively gabapentinoids, are primarily anticonvulsant drugs. Over the past decade, they have been increasingly prescribed for pain. 1 They are recommended for neuropathic pain in adults 2 3 (table 1), but are commonly used off-label for other pain disorders such as low back pain, sciatica, and migraine. 9 10 ...
Indications for anticoagulant and antiplatelet combined therapy
WEBOct 5, 2017 · Antithrombotic medications reduce thromboembolic events by inhibiting platelet aggregation and coagulation. Antiplatelet drugs and oral anticoagulants are examples of antithrombotic medications and are among the most commonly prescribed drugs in both primary and secondary care. 1 Clinicians are familiar with their use, however antiplatelets and ...
Management of acute upper gastrointestinal bleeding | The BMJ
WEBMar 25, 2019 · Upper gastrointestinal bleeding (UGIB) is a common medical emergency, with a reported mortality of 2-10%. Patients identified as being at very low risk of either needing an intervention or death can be managed as outpatients. For all other patients, intravenous fluids as needed for resuscitation and red cell transfusion at a hemoglobin threshold of 70-80 g/L are recommended. After ...
Postural hypotension - The BMJ
WEBApr 23, 2021 · Postural hypotension is a drop in blood pressure (≥20 mm Hg systolic and/or ≥10 mm Hg diastolic) that occurs within 3 minutes of standing. Test for it in people who have symptoms of lightheadedness or dizziness on changing from lying or sitting to standing posture or those with an unexplained fall. …
Writing a case report in 10 steps - The BMJ
WEBMay 27, 2015 · Writing up. Write up the case emphasising the interesting points of the presentation, investigations leading to diagnosis, and management of the disease/pathology. Get input on the case from all members of the team, highlighting their involvement. Also include the prognosis of the patient, if known, as the reader will want to know the outcome.
Investigating raised creatine kinase | The BMJ
WEBJun 23, 2021 · A 76 year old man with hypercholesterolaemia is referred to the lipid clinic because of persistently raised creatine kinase activity of 1000 IU/L or above (reference range 40-320 IU/L) after trying multiple statins. He describes no significant myalgia but had some proximal muscle weakness, which is demonstrated when he stands up from a seated position and when walking upstairs.
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