A suspected attack by Yemen’s Houthi rebels has targeted a ship in the Red Sea. The incident Tuesday likely marks their first assault on commercial shipping in weeks as the Israel-Hamas war threatens to become a regional conflict.

DUBAI, United Arab Emirates (AP) — Yemen’s Houthi rebels claimed Monday they shot down another American-made MQ-9 Reaper drone over the country, with videos purportedly showing a surface-to-air missile striking it. The U.S. military did not immediately acknowledge losing any aircraft.

The strikes in Yemen attacked Ras Issa and the port city of Hodeidah, the Israeli military said. The Houthi rebel group said Israel targetted fuel tanks and two power stations.

Israel said it bombed Houthi targets in Yemen on Sunday in response to missile fire by the Iran-aligned militants at Israel over the past two days, marking another front in fighting in the Middle East.

A drone boat loaded with explosives crashed into a ship Tuesday in the Red Sea, the British military and private security officials said, the latest suspected attack by Yemen’s Houthi rebels. The drone attack and an earlier attempted attack Tuesday likely are the rebels’ first assaults on commercial shipping in weeks as the Israel-Hamas war threatens to become a regional conflict.

Israel launched strikes at Houthi targets in Yemen on Sunday after the Houthi militants fired missiles at Israel over the past two days, marking a fresh exchange in another front of the regional conflict.

An explosive-loaded drone crashed into one ship Tuesday in the Red Sea as a missile exploded against another, the British military and private security officials said, marking the latest suspected attacks by Yemen’s Houthi rebels.