Leslie Charleson, the soap-opera legend who played Monica Quartermaine on 'General Hospital' starting in the 1970s, died Sunday. She was 79.

Soap opera icon Leslie Charleson, best known as Monica Quartermaine on "General Hospital," died Sunday morning after a long illness. She was 79.

Leslie Charleson, who played Dr. Monica Bard Webber Quartermaine on General Hospital for over 45 years, has died at the age of 79. The fan favorite played out many memorable storylines over the years — here’s a look back at some of the ABC soap’s best Monica Quartermaine moments.

Ms. Charleson played Dr. Monica Quartermaine, a cardiologist and family matriarch, on the daytime series for 46 years.

General Hospital star Leslie Charleson's death rocked the soap world on the evening of January 12. The actress was a GH mainstay since 1977 and had been beloved by co-stars and fans alike.

Soap opera veteran Leslie Charleson, who played Monica Quartermaine on "General Hospital," has died at the age of 79.

Leslie Charleson, who played popular character Dr. Monica Quartermaine for almost 50 years on “General Hospital,” has died. She was 79.

Leslie Charleson, who played popular character Dr. Monica Quartermaine for almost 50 years on "General Hospital," has died, the program's executive producer announced on Sunday.She was 79."

It looks like General Hospital is due for a big shift in the Quartermaine family dynamics. The legendary Leslie Charleson, who played Monica for nearly 50 years, has unfortunately passed away. She’s bravely led the Quartermaine clan now for years,

General Hospital’s Jason recently sided with Tracy and the Quartermaines over Sonny. Will his loyalty wind up netting him a big surprise gift?

Wally Kurth joined General Hospital in 1991 as Ned Ashton, a member of the Quartermaine family — so Ned enjoyed a close relationship with his aunt, Monica Quartermaine, played by Leslie Charleson, who passed away on January 12,

General Hospital” star Leslie Charleson died at 79 and fans are reacting to the news by sharing their love for the actress across social media.