The Lions will face a 49ers offensive line that could be starting two tackles signed off practice squads this week ...

BYU AD Tom Holmoe was once Deion Sanders’ position coach with the 49ers. Thirty years later, the two will meet again in the ...

Unlike in previous seasons, the Arizona quarterback's running ability has evolved into a complementary piece of the offense ...

This isn't the same 49ers team the Lions lined up against 11 months ago, but Detroit is still treating it like a marquee game ...

The Lions can clinch the NFC North title with a win over the 49ers on Monday if the Packers upset the Vikings.

Mahomes is not only one of the most clutch players ever, with a shortstop’s arm and range, but also one of the toughest ...

The 29-17 loss to the Dolphins perfectly encapsulated the campaign: statistically strong but fundamentally rotten. On Sunday, ...

Samuel looked like his old self on Sunday, breaking tackles, dragging defenders and making critical plays while chipping in ...

The defending NFC champion San Francisco 49ers were eliminated from the playoffs before their game at Miami began on Sunday ...

The 49ers (6-9) became the 16th team to miss the postseason after losing the previous Super Bowl. They fell 25-22 to the ...

On the day the San Francisco 49ers were officially eliminated from playoff contention, they delivered a performance that ...

San Francisco 49ers running back Isaac Guerendo is expected to return from foot and hamstring injuries and play Monday, a ...