Week 4 of college football brings more uniform heat with deep meanings. After losing to the Missouri Tigers in Week 3, who knocked them out of the AP Top-25 rankings, the Boston College Eagles are looking for vengeance Saturday when they take on the Michigan State Spartans.

Seventh-ranked Missouri opens SEC play against Vanderbilt on Saturday. The Tigers are coming off a win over then-No. 24 Boston College in which they were slow at the start but came on strong, and ultimately overcame three unsportsmanlike conduct penalties.

Missouri defeated the 24th-ranked Eagles 27-21 in a hard-fought affair that featured an 11-point comeback from the Tigers, who relied on a pair of turnovers to spark their rebound. Chief among those was fifth-year safety Tre’Vez Johnson’s second-quarter interception that flipped the momentum back to the Missouri side.