The Detroit Lions (13-2) are headed out west to face off against Brock Purdy and the San Francisco 49ers on Monday Night ...

One reason the 49ers haven't been good this season is their inability to create turnovers on defense. It's been an issue, especially in their last month of gam ...

The Lions (13-2) head into the rematch Monday night with the inside track at the top seed in the NFC playoffs, while the 49ers (6-9) have already been ... their final two games or with a win against ...

On NBC Sports Bay Area's "49ers Game Plan," San Francisco coach Kyle Shanahan expressed his desire for the 49ers to play ...

San Francisco 49ers head coach Kyle Shanahan addressed reporters on Saturday following the team's final practice before their ...

The 49ers will have running back Isaac Guerendo for Monday Night Football. Guerendo, who missed last week’s game with a hamstring injury, does not have an injury designation for the game against the ...

Justin Herbert threw three touchdown passes and the Los Angeles Chargers clinched their second playoff appearance in three seasons with a 40-7 victory over the New England Patriots on Saturday.

NFL Week 17 matchups, odds, picks and props following Christmas Day games. Three Saturday contests followed by Sunday's most ...