Learn about SPRAVATO® (esketamine) nasal spray, a prescription medicine for two indications. See full Prescribing & Safety Info, including BOXED WARNINGS.

SPRAVATO ® offers a different approach and is the only FDA-approved nasal spray treatment for treatment-resistant depression (TRD)

Before you take SPRAVATO®, talk to your healthcare provider about your full medical and depression treatment history, including if you have a history of abusing prescription or street …

SPRAVATO® Risk Evaluation and Mitigation Strategy (REMS). Because of the risks for sedation, dissociation, respiratory depression, and abuse and misuse, SPRAVATO ® is only available through a restricted program called the SPRAVATO ® Risk Evaluation and Mitigation Strategy (REMS) Program.

You will administer SPRAVATO ® nasal spray yourself under the supervision of a healthcare provider at a certified SPRAVATO ® treatment center. Your healthcare provider will show you …

Getting Started on SPRAVATO ® If you have treatment-resistant depression (TRD), you may benefit from taking SPRAVATO ® with or without an oral antidepressant. Start the conversation with your doctor to see if adding SPRAVATO ® may be right for you, and discover more about what the full SPRAVATO ® treatment experience could look like for you.

The key steps are outlined below, from how to get started on SPRAVATO®, to ways to pay for your treatment, and what you can expect on your treatment journey.

SPRAVATO ® can only be administered at healthcare settings certified in the SPRAVATO ® REMS Program. Patients treated in outpatient healthcare settings (such as medical offices and …

PROGRAM REQUIREMENTS APPLY. Get savings on your out-of-pocket medication costs for SPRAVATO®. Depending on your health insurance plan, savings may apply toward co-pay, co-insurance, or deductible. Program does not cover the cost of treatment observation. SPRAVATO® is a prescription medicine, used along with an antidepressant taken by mouth to ...

SPRAVATO® is a prescription medicine, used along with an antidepressant taken by mouth to treat: in (anesthetic). It is not known if SPRAVATO® is safe or efective as an ane