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Use of progestogens and the risk of intracranial meningioma: national case-control study. 2. Association of holidays and the day of the week with suicide risk: multicounty, two stage, time series study. 3. Effect of exercise for depression: systematic review and network meta-analysis of randomised controlled trials. 4.
Vitamin B12 deficiency: NICE guideline summary | The BMJ
Jun 13, 2024 · Vitamin B 12 deficiency is associated with a range of symptoms and signs, resulting in substantial variation in patient presentation. While epidemiological data are limited, cross sectional studies from the UK and US suggest a prevalence of 3% in people aged 20-39, increasing with age up to about 20% in people aged 85 and over.1 2 Complications of vitamin …
Strengthening the basics: public health responses to prevent the …
Nov 29, 2021 · Victoria Haldane and colleagues argue that to make covid-19 the last pandemic, public health responses to outbreaks must be strengthened, starting with their most basic functions The covid-19 pandemic has challenged countries to mount and sustain comprehensive public health responses that identify and control an emerging infectious hazard. These …
Chronic obstructive pulmonary disease: diagnosis and ... - The BMJ
Jul 29, 2019 · There are 1.3 million people in the UK with a diagnosis of chronic obstructive pulmonary disease (COPD) and the condition is responsible for considerable morbidity and mortality. 1 COPD is also a common cause of hospital admission. NHS England has now recognised respiratory disease as a priority area in the Long Term Plan, 2 but Royal College of …
Low back pain and sciatica: summary of NICE guidance - The BMJ
Jan 6, 2017 · Low back pain is the leading cause of long term disability worldwide. 1 The lifetime incidence of low back pain is 58-84%, 2 and 11% of men and 16% of women have chronic low back pain. 3 Back pain accounts for 7% of GP consultations and results in the loss of 4.1 million working days a year. 2 More than 30% of people still have clinically significant symptoms after …
Vitamin B12 - The BMJ
Nov 20, 2023 · ### What you need to know Vitamin B12 (cobalamin) is a water soluble vitamin required for several physiological processes, including normal nervous system functioning, and red blood cell development and maturation. It has antioxidant effects, is a co-factor in mitochondrial energy metabolism, and contributes to DNA synthesis, the methylation cycle, …
Management of depression in adults: summary of updated NICE …
Jul 20, 2022 · Since the National Institute for Health and Care Excellence (NICE) published its last guideline on depression in 2009,1 the prevalence of depression has increased,2 particularly among vulnerable adults during the covid-19 pandemic.3 Yet fewer than half of people affected receive treatment,2 despite increased provision of psychological therapies4 and …
Latest guidance on the management of gout | The BMJ
Jul 18, 2018 · Gout is the most common inflammatory arthritis and its incidence in the UK has steadily increased from 1.5% in 1997 to 2.5% in 2012. 1 2 It is characterised by deposition of monosodium urate crystals in joints and tissues and usually presents with intermittent painful attacks followed by long periods of remission. 3 Here, we review the latest ...
Lack of physical activity is a global problem | The BMJ
Feb 23, 2022 · Primary care is an essential partner in the response Physical activity has been more important than ever during the covid-19 pandemic. Insufficient physical activity is a global health problem and has itself been called a pandemic.1 Lockdowns have reduced time spent on physical activity and increased sedentary time,23 both of which are associated with risks to …
Management of pneumonia in critically ill patients | The BMJ
Dec 6, 2021 · Severe pneumonia is associated with high mortality (short and long term), as well as pulmonary and extrapulmonary complications. Appropriate diagnosis and early initiation of adequate antimicrobial treatment for severe pneumonia are crucial in improving survival among critically ill patients. Identifying the underlying causative pathogen is also critical for …